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Year : 2022  |  Volume : 19  |  Issue : 4  |  Page : 671-675

Relationship between vitamin D3 level and body mass index in postmenopausal breast cancer patients

1 Department of Molecular Biology, General Health Laboratory, Nineveh Health Dorectorate, Mosul, Iraq
2 Department of Internal Medicine, College of Medicine, University of Mosul, Mosul, Iraq
3 Department of Pathology, College of Medicine, Nineveh University, Mosul, Iraq
4 Center for Gene Diagnosis, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China

Correspondence Address:
Alya A Al Zobair
Department of Internal Medicine, College of Medicine, University of Mosul, Mosul 00964
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/MJBL.MJBL_207_22

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Background: Many studies have shown a relation between vitamin D3 deficiency and breast cancer, others estimated an inverse correlation between vitamin D3 and obesity. Objectives: This study aimed to verify the relation between vitamin D3 level and obesity in postmenopausal breast cancer patients. Materials and Methods: This is a cross-sectional study included seventy-six postmenopausal patients with breast cancers who were diagnosed in the period from January 2020 to February 2022 who were divided into two groups: patients with body mass index (BMI) ≥ 30 and those patients with BMI <30. Vitamin D3 level was estimated and compared between the two groups. We studied the correlation between vitamin D3 level with the age of the patients and the parity. Results: the mean age of the included patients was 61 ± 7.7 years and the mean BMI was 32.3 ± 4.3g/m2. The mean value of vitamin D3 was 15. 0 ± 5. 4 for the patients with BMI ≥ 30 while it was 18.2 ± 4.3 for those patients with BMI <30 and there was a significant difference between the two groups with P = 0.007. Furthermore, patients’ vitamin D3 levels showed significant inverse correlations with their age (P = 0.008) and BMI (P = 0.001). Conclusion: There is consistent evidence that deficiency of vitamin D3 is associated with obesity in breast cancer postmenopausal patient; also, vitamin D3 level has a negative correlation with the age and parity of the patients.

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