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Year : 2022  |  Volume : 19  |  Issue : 4  |  Page : 653-658

Study the profile of some antioxidant markers in diabetic mellitus and non-diabetic patients with cardiovascular disease

Department of Chemistry, College of Science, University of Kirkuk, Kirkuk, Iraq

Correspondence Address:
Israa Ghassan Zainal
Department of Chemistry, College of Science, University of Kirkuk, Kirkuk
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/MJBL.MJBL_190_22

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Background: Cardiovascular diseases (CVDs) claim the lives of millions worldwide. Objective: Evaluate the levels of some antioxidant biomarkers in sera of patients with CVDs with and without diabetes mellitus type 2. Materials and Methods: Includes 100 samples in 68 patients (40 with CVDs and 28 CVDs with diabetic), and 32 healthy subjects. Results: Serum (Albumin, thiol, thiol/T.protein, amine, free amine/ T.protein, carbonyl, carbonyl/ T.protein, and Ischemia modified albumin (IMA)) showed a stronger response, a significant rise in carbonyl and carbonyl/TP, and a significant reduction in thiol and thiol/TP in the patients with CVDs with T2D compared to CVDs may be a good factor to differentiate them or predict more serious complications. Conclusions: Oxidation markers may be useful in monitoring CVDs with and without diabetes.

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