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REVIEW ARTICLE
Year : 2022  |  Volume : 19  |  Issue : 4  |  Page : 514-517

Role of PAD enzymes on histone citrullination in cancer


1 Clinical Pharmacy Department, College of Pharmacy, University of Basrah, Basrah, Iraq
2 Clinical Laboratory Sciences, College of Pharmacy, University of Baghdad, Baghdad, Iraq

Correspondence Address:
Noor Mohammed Abdulrahman
Clinical Pharmacy Department, College of Pharmacy, University of Basrah, Basrah
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/MJBL.MJBL_148_22

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Citrullination process is a natural pathway which happened at the time of cell dying, but during removal of these products, PAD enzymes may release causing stimuli to the immune system. This can start a consequence of processes and enhancement of cancer disease. In this review, we will focus on this marker and significance of its application for early detection of cancer and for follow-up disease, and the latest approved medications act on this line.


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