| REVIEW ARTICLE |
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| Year : 2022 | Volume
: 19
| Issue : 4 | Page : 514-517 |
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Role of PAD enzymes on histone citrullination in cancer
Noor Mohammed Abdulrahman1, Shatha Hussein Ali2
1 Clinical Pharmacy Department, College of Pharmacy, University of Basrah, Basrah, Iraq
2 Clinical Laboratory Sciences, College of Pharmacy, University of Baghdad, Baghdad, Iraq
Correspondence Address:
Noor Mohammed Abdulrahman
Clinical Pharmacy Department, College of Pharmacy, University of Basrah, Basrah
Iraq
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/MJBL.MJBL_148_22
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Citrullination process is a natural pathway which happened at the time of cell dying, but during removal of these products, PAD enzymes may release causing stimuli to the immune system. This can start a consequence of processes and enhancement of cancer disease. In this review, we will focus on this marker and significance of its application for early detection of cancer and for follow-up disease, and the latest approved medications act on this line. |
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