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Year : 2021  |  Volume : 18  |  Issue : 4  |  Page : 443-444

Severe systemic allergic reaction after topical application of mupirocin

Arth Hospital, Palghar, Maharashtra, India

Correspondence Address:
Adesh Mishra
Arth Hospital, Rashmi Villa No. 1, Vasant Nagri, New Link Road, Near Agarwal Circle, Vasai East, Palghar 401208, Maharashtra.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/MJBL.MJBL_41_21

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Mupirocin (MUP) is a natural derivative of crotonic acid extracted from Pseudomonas fluorescens. This antibiotic has a unique chemical structure and mechanism of action.It is often used topically for the treatment of cutaneous infections to prevent skin and soft tissue infections caused by S. aureus isolates and where the MRSA isolates are epidemic. Furthermore, MUP may be used as a choice drug for nasal decolonization.Despite some side effects, mupiro¬cin has been reported to be safe and to cause allergic reactions in only extremely rare cases. This paper is a report on a rare case of severe systemic allergic reaction resulting from treatment with mupirocin ointment in a 39 year old male patient who had a history of burn injury.

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